US stocks plummeted on Friday in the wake of the United Kingdom’s vote to leave the European Union, triggering a global sell-off as investors grappled with the potential economic fallout.

The Dow Jones Industrial Average suffered its worst day since August, dropping more than 600 points. The S&P 500 and Nasdaq also experienced substantial losses, reflecting broad market anxiety.

Analysts cited concerns about the impact of Brexit on international trade, economic growth, and corporate earnings as key drivers of the market decline. The financial sector was particularly hard hit, with bank stocks taking a major tumble.

The uncertainty surrounding the future relationship between the UK and the EU, as well as the potential for other countries to follow suit, fueled investor nervousness. Many are now seeking safe-haven assets, such as gold and US Treasury bonds.

Market volatility is expected to continue in the coming days as investors assess the long-term implications of Brexit.