Form 8.3 - Avadel Pharmaceuticals plc

FORM8.3

IRISHTAKEOVERPANEL

DISCLOSUREUNDERRULE8.3OFTHEIRISHTAKEOVERPANEL ACT,1997,TAKEOVERRULES,2013

DEALINGSBYPERSONSWITHINTERESTSINRELEVANTSECURITIESREPRESENTING1%ORMORE

1. KEYINFORMATION

Nameofpersondealing(Note1)State Street Global Advisors & AffiliatesCompanydealtinAvadel Pharmaceuticals plcClassofrelevantsecuritytowhich
the dealingsbeingdisclosedrelate(Note2) $0.01 ordinary sharesDateofdealing6th November 2025

2. INTERESTSANDSHORTPOSITIONS
(110) Interestsandshortpositions(followingdealing)intheclassofrelevantsecurity dealtin (Note 3)

LongShort Number(%)Number(%)(1)Relevantsecurities2,276,1492.33683% (2)Derivatives(otherthanoptions)N/AN/A (3)Optionsandagreementsto
purchase/sellN/AN/A Total2,276,1492.33683%

(b) Interestsandshortpositionsinrelevantsecuritiesofthecompany,other thanthe classdealtin (Note 3)

Classofrelevantsecurity:LongShort Number(%)Number(%)(1)RelevantsecuritiesN/A (2)Derivatives(otherthanoptions)N/A (3)Optionsandagreementstopurchase/sellN/A TotalN/A

3. DEALINGS (Note 4)
(110) Purchasesandsales

Purchase/saleNumberofrelevantsecuritiesPriceperunit (Note 5)Sale4518.71

(b) Derivativestransactions(otherthanoptionstransactions)

Productname,
e.g.CFDNatureoftransaction

(Note 6)Numberofrelevantsecurities

(Note 7)Priceperunit

(Note 5)N/A

(c) Optionstransactionsinrespectofexistingrelevantsecurities

(i) Writing,selling,purchasingorvarying

Productname,
e.g.calloptionWriting,selling,
purchasing
varyingetc.Numberof
securities towhich
theoption relates
(Note 7)Exercise
priceType,e.g.
American,
Europeanetc.Expiry
dateOptionmoney
paid/received
perunit (Note 5)N/A

(ii) Exercising

Productname,
e.g.calloptionNumberofsecuritiesExercisepriceper
unit (Note 5)N/A

(d) Otherdealings(includingtransactionsinrespectofnewsecurities)(Note4)

Natureoftransaction
(Note 8)DetailsPriceperunit
(ifapplicable) (Note 5)N/A

4. OTHERINFORMATION
Agreements,arrangementsorunderstandingsrelatingtooptionsorderivatives

Fulldetails of any agreement, arrangement or understanding betweenthepersondisclosing andanyotherpersonrelatingtothevotingrightsofanyrelevantsecuritiesunderanyoption referredtoonthisform or relating to the voting rights or future acquisition or disposal ofany relevantsecuritiestowhichanyderivativereferredtoonthisformisreferenced.Ifnone,this shouldbestated.N/A

IsaSupplementalForm8attached? (Note 9)
NO
Date of disclosure
7th November 2025

Contactname
Divya K
Telephonenumber

+918067452364

IfaconnectedEFM,nameofofferee/offeror withwhichconnected
N/A
IfaconnectedEFM,statenatureof connection (Note 10)
N/A