Protagonist Therapeutics (NASDAQ:PTGX [https://seekingalpha.com/symbol/PTGX]), a biotech focused on peptide-based therapeutics, traded ~30% higher on Friday after The Wall Street Journal reported that Johnson & Johnson (NYSE:JNJ [https://seekingalpha.com/symbol/JNJ]) is in talks to acquire the company.
Citing people familiar with the matter, the publication noted that the deal, details of which were not yet finalized, is expected to consolidate JNJ’s (NYSE:JNJ [https://seekingalpha.com/symbol/JNJ]) existing partnership with the Newark, California-based company.
A final agreement is not guaranteed, the people said, adding that the terms of the deal being discussed couldn’t be obtained.
A potential transaction is expected to well surpass Protagonist’s (NASDAQ:PTGX [https://seekingalpha.com/symbol/PTGX]) market capitalization of roughly $4B, including a deal premium, and boost JNJ’s portfolio of immune and cancer drugs with two experimental drugs.
The companies are currently in pact to develop an oral therapy for [https://www.wsj.com/health/pharma/johnson-johnson-in-talks-to-buy-protagonist-therapeutics-38e0b69d] immune diseases, including plaque psoriasis and ulcerative colitis, with JNJ having an exclusive license to commercialize the product.
With the deal, the New Jersey-based pharma giant, which already owns 4% of its partner, is expected to add another experimental therapy called rusfertide, developed by Protagonist (NASDAQ:PTGX [https://seekingalpha.com/symbol/PTGX]) and Takeda (TAK [https://seekingalpha.com/symbol/TAK]).
Rusfertide has shown potential in a rare blood cancer called polycythemia vera in late-stage development.
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J&J reportedly in talks to buy Protagonist
Published 1 month ago
Oct 10, 2025 at 3:36 PM
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